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More recent evidence indicates that sustained GIP receptor agonism in the presence of GLP-1 activation enhances insulin sensitivity and may preferentially reduce visceral adipose tissue

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Activin receptor-like kinase 7 suppresses lipolysis to accumulate fat in obesity through downregulation of peroxisome proliferator-activated receptor and C/EBP

The Diabetes Prevention Program was a large, long-term study enrolling people with pre-diabetes, with one arm using metformin

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